This percentage may be even higher as fentanyl can easily be mixed with other drugs, often without the user’s knowledge, which has made it particularly dangerous. Because fentanyl is about 50 to 100 times more potent than morphine, even a very small dose of fentanyl can be deadly. Using a drug that has been contaminated with or replaced by fentanyl can greatly increase the risk of a life-threatening overdose. However, an emergency medicine called naloxone can reverse an opioid overdose related to fentanyl.

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When it’s in powdered form, it looks a lot like other powdered drugs such as cocaine. Powdered fentanyl can also be pressed into pills that look like prescription pills such as Percocet or Xanax. People sell illegal fentanyl as a powder, dropped onto blotter paper, put in eye droppers and nasal sprays, or as pills that look like other prescription opioids.
Fentanyl Addiction

Fentanyl is a powerful opioid pain medication as well as a common contaminant found in illicit drugs. The antidote naloxone (Narcan) can reverse the effects of a fentanyl overdose if given in time. In addition to receiving treatment for a substance use disorder, people who use illegal drugs can help prevent overdoses by using fentanyl test strips. These are low-cost paper strips that can detect fentanyl in all kinds and forms of substances. Fentanyl is typically administered intravenously (IV), intramuscularly (IM), transdermally (TD) as skin patches, intranasally (IN) in the form of a volatile nasal spray, and intrathecally (IT).
How Does Fentanyl Affect The Body?
A doctor may also choose to prescribe naltrexone, which stops the effect fentanyl has on the body. A person with a substance use disorder might obtain fentanyl by misusing prescribed medication or acquiring the drug from an illegal laboratory. Misuse of fentanyl includes taking it orally, smoking it, snorting it, or injecting it.
- The report was critical of the U.S Postal Service and the U.S.
- The FDA has approved these antidote medications for emergency treatment of patients with known or suspected opioid overdose experiencing respiratory and/or central nervous system (CNS) depression.
- Facts about fentanyl use and abuse, as well as recognizing signs of overdose symptoms, are crucial for those who aim to provide support.
- That is, in combination with certain neuroleptic medications as part of therapeutic neuroleptanalgesia.
We encourage our clients to engage with aftercare support and pave their paths to long-term sobriety through ongoing counseling, support groups, and lifestyle changes. This comprehensive approach to recovery gives people struggling with fentanyl addiction real hope and healing. Facing the reality of a loved one’s fentanyl addiction is an emotional challenge. Facts about fentanyl use and abuse, as well as recognizing signs of overdose symptoms, are crucial for those who aim to provide support.
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It remains one of the most commonly used opioids in controlled medical settings or advanced cancer pain. Fentanyl also can increase feelings of pleasure, often referred to as euphoria. Other effects can include drowsiness, nausea, confusion, constipation and addiction. Fentanyl can be illegally mixed into other substances, including heroin, cocaine, ecstasy, and methamphetamine (NIDA, 2021). This combination can result in an individual consuming a much stronger substance than they are used to, resulting in overdose and possibly death.

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The DEA has found an average of 2.4 milligrams of fentanyl in the pills they test (DEA, 2024). Fentanyl is a synthetic opioid that can be prescribed by doctors for pain management (National Institute on Drug Abuse NIDA, 2021). It is also increasingly found mixed into street drugs (Drug Enforcement Administration DEA, 2024). Understanding the dangers of fentanyl is crucial, especially for individuals who might unknowingly consume it or use it without a doctor’s prescription.

Pharmaceutical fentanyl is rigorously controlled and legally prescribed, often in the form of patches or lozenges. Education about the risks of fentanyl use, increased access to naloxone, and comprehensive addiction treatment programs are crucial in addressing this crisis. If you or someone you know is struggling with fentanyl use, it is essential to seek professional help.
National Coalition Against Prescription Drug Abuse
- Fentanyl can also be “diverted.” That’s when the drug is prescribed by a doctor but isn’t used as directed or is sold or given to someone else.
- You also have trouble feeling pleasure from anything besides the drug.
- Doctors will only prescribe the fentanyl patch to people who are already tolerant of opioid therapy that is similar in strength.
- They have been working on this investigation since last year, and their full findings will be reviewed at a Senate hearing on Thursday.
- If you suspect someone is experiencing an overdose, the CDC recommends following the steps below.
Due to high levels of stress, first responders and health care workers are at risk for substance use disorders. The Heroes Helpline is a free, confidential, telephone support line available to EMS and health care workers. Callers can access free peer support, learn how to navigate treatment and referral services, and receive information on employment and licensing concerns. Overdose deaths involving fentanyl have quadrupled in recent years. Because of the so-called “War on Drugs” and criminalization of people who use drugs, people often are unaware of the exact composition of the substances they’re using. This makes evidence-based harm reduction strategies such as fentanyl test strips, safety planning, and access to safe supply more vital than ever.

Opioid medication enters the brain and binds to opioid receptors, restricting pain signals and causing relaxation (Oesterle, 2021). Low doses of opioids can make a person sleepy, but larger doses can cause heart rate and breathing to slow down significantly, resulting in unconsciousness. There are two types of fentanyl – pharmaceutical fentanyl and illegally made fentanyl. Because the drug is less expensive than other opioids, people making it illegally commonly mix it into drugs such as heroin, cocaine, or methamphetamines.
Naloxone: Overdose Reversal Drug
Fentanyl test strips are vital harm-reduction tools that detect the presence of fentanyl in drug samples. They’re easy to use— just mix a sample with water and dip the strip — and they provide quick information about potentially dangerous drugs. Methamphetamine laced with fentanyl is another high-risk combination. The stimulant effects of methamphetamine can mask the depressant effects of fentanyl, leading to accidental overdoses.
It comes in both pharmaceutical and non-pharmaceutical forms. Accidental opioid overdoses cause more deaths in the United States than traffic accidents and suicides, she noted in a university news release. “People are struggling from the effects of addiction,” said Tiffany Champagne-Langabeer, senior author of a new investigation of illegal drug sales.
As little as 2 milligrams or less may cause death, which is about the size of a few grains of salt. If you unknowingly take fentanyl in another drug, you may overdose since fentanyl is so potent. Withdrawal symptoms typically start within 12 hours after your last dose of the drug. The first 3 days are the hardest, with the most severe symptoms.
Fentanyl Is Available In A Variety Of Forms
“A lot of people have used drugs that have flowed through cryptomarkets without knowing what cryptomarkets are,” he said. One such individual was a 49-year-old Ohioan who sent roughly $2,500 to an online seller over the course of 10 months—from May 2016 to February 2017. Over that time period, he received 15 packages through the Postal Service on dates that closely corresponded to payments he made to an online seller. He died in early 2017 from “acute fentanyl intoxication.” He had received a package from an online seller just 30 days before his death.
Drug Overdose Deaths Remain High Fentanyl Test Strips May Help
You can get them free through some outreach programs, such as needle exchanges or overdose prevention programs. The medication will reverse the effects of fentanyl and block future effects. If a person appears to experience overdose symptoms again, they may require another dose.