If someone with a substance use disorder is unaware of the added fentanyl, this can put them at a higher risk of accidental overdose or death. Misusing fentanyl, such as taking it without a prescription or in higher doses than prescribed, can have serious consequences. In fact, fentanyl is a major contributor to the opioid crisis in the United States, leading to thousands of overdose deaths each year. It works against all opioids, including fentanyl, a heroin-like drug that can be lethal in small doses. Fentanyl is one of the top substances driving overdose deaths in the US, according to the Centers for Disease Control and Prevention. Fentanyl is often mixed with other drugs like heroin, crack, or cocaine.

Older Black Men Are Disproportionately Affected By The Overdose Crisis
As these are unofficial terms, they can rapidly change and vary from region to region. Healthcare providers, law enforcement, and the public should stay aware of these changes. The American Society of Health-System Pharmacists®, 4500 East-West Highway, Suite 900, Bethesda, Maryland.
NIH-funded Intervention Did Not Impact Opioid-related Overdose Death Rates Over Evaluation Period

These are people who have taken another opioid pain drug that no longer works as well. It comes in both pharmaceutical and non-pharmaceutical forms. They found people who were purchasing for personal use — including seven who overdosed and died — as well as the people buying to set up their own distribution network in America.
- Opioids are a class of drugs that include both prescription medicines such as morphine and illegal drugs like heroin.
- As with other opioid drugs, fentanyl binds to the receptors in the brain that affect pain and emotion.
- Do not let anyone else use your medication, even if he or she has the same symptoms that you have.
- These small, paper strips can be obtained at needle-exchange sites, are easy to use and only take minutes to interpret.
- Thus, consumers may unknowingly ingest fentanyl, increasing the risk of overdose and death.
- With the popularity of drug dealers mixing fentanyl into other drugs, fentanyl test strips can help people who use drugs identify whether what they are taking contains fentanyl or not.
Fentanyl is used as needed to treat breakthrough pain but not more often than four times a day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. “Fentanyl is in the supply of many drugs on the street,” explains Dr. Donald. “It took time to create this opioid epidemic, and it is taking time as we learn how to best combat it. There is hope, and there is treatment that works, is safe and is effective.” Help educate your loved one on the risks of fentanyl and make sure they know these harm reduction strategies. When it is intentionally misused, fentanyl often shows up as a powder, spiked on blotter paper or is mixed with or substituted for heroin and other street drugs.
Treating Fentanyl Addiction

Below is a list of medications that can interact with fentanyl. This list doesn’t contain all drugs that may interact with fentanyl. After your first dose and when your doctor increases your doses of fentanyl, you may have a drop in blood pressure. Your doctor may have you check your blood pressure during these time periods. To help prevent or treat constipation while taking fentanyl, talk to your doctor about dietary changes, laxatives (drugs that treat constipation), and stool softeners.
Public Health

This article focuses on injectable fentanyl; more detailed coverage of the transdermal formulation is available in the StatPearls specific article on transdermal fentanyl. Naloxone (Narcan) now available by request from your pharmacist or by mail. Naloxone can reverse an overdose from opioids, including heroin, fentanyl and prescription opioid medications. You don’t need to visit a physician or medical provider to keep this emergency medication on hand. Your pharmacist will provide a prescription by request, or you can have the Mississippi State Department of Health mail a naloxone kit directly to you at no cost.
Poison Control Media Information
Your doctor or pharmacist will show you and your family members how to use the medication. Ask your pharmacist for the instructions or visit the manufacturer’s website to get the instructions. Your symptoms may return within a few minutes after you receive naloxone. If your symptoms return, the person should give you another dose of naloxone. Additional doses may be given every 2 to 3 minutes, if symptoms return before medical help arrives.
What Should You Ask Your Health Care Professional Before Taking Opioids?
The dose for pharmaceutical fentanyl depends on how it is given and the patient’s pain level. Fentanyl patches offer a continuous dose and last 72 hours. According to the National Institute of Health, the normal IV dose for post-operative pain control is 50 to 100 mcg every 1 to 2 hours as needed. The liquid form is often dropped on paper or small candy, leading to the potential for tragic deaths among children. Due to its potency, it has a high potential for addiction and overdose.
A doctor may prescribe laxatives with opioids to help prevent constipation. Fentanyl transdermal patch may be used as part of a combination therapy. Recently, drug seizures have found brightly colored pills laced with fentanyl, also known as rainbow fentanyl.

If you suspect someone is overdosing on fentanyl, call emergency services immediately. If available, administer naloxone, a medication that can rapidly reverse opioid overdose. Fentanyl is in a class of medications called narcotic (opiate) analgesics. It works by changing the way the brain and nervous system respond to pain. Fentanyl is 100 times stronger than morphine and 50 times stronger than heroin (DEA, n.d.). It is so potent that just 2 milligrams can cause someone to experience a fatal overdose (DEA, 2024).
Fentanyl, Transdermal Patch Images
The staff started, quite literally, by Googling “fentanyl for sale,” they said. Posing as first-time buyers, they made contact with six responsive sellers. These sounded like sophisticated operations, offering discounts on bulk purchases and even trying to upsell the investigators to carfentanil, an even more powerful opioid.
Fentanyl is a powerful synthetic opioid that is commonly used to treat severe pain. However, due to its high potency, fentanyl also has a high potential for misuse and abuse. This has led to concerns about whether or not it can be purchased over the counter. The symptoms of a fentanyl overdose are the same as any other opioid overdose, even though they may come on more quickly due to the drug’s potency. In general, opioid overdoses occur about one to three hours after the drug is ingested, according to the New York State Department of Health.
Recovery is possible with the proper support and treatment. People taking a daily prescribed dose will become dependent on the drug and will have withdrawal symptoms if they stop it. This is not an addiction but instead a physiological response.
As a result, more than 150 people in the US die every day from overdoses related to fentanyl or similar synthetic opioids, according to the CDC. On Wednesday, the FDA announced that it has approved the sale of naloxone nasal spray, also known as Narcan, for sale over-the-counter to treat opioid overdose. Previously, the medication had only been available by prescription. Now, the agency said, it will be sold at drug stores, grocery stores, gas stations, and online within the next several months. It must be introduced into the bloodstream or a mucus membrane in order for someone to feel the effects. While there are fentanyl patches that can be placed on the skin for pain management, this is not the formulation that’s cut into other substances.