It can be harmful for people to use Fentanyl (Fentanyl-transdermal) if their doctor has not prescribed it. Your doctor may have suggested Fentanyl (Fentanyl-transdermal) for conditions other than those listed in these drug information articles. If you have not discussed this with your doctor or are not sure why you are using Fentanyl (Fentanyl-transdermal), speak to your doctor.
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Naloxone — also known by the brand names such as Narcan and Kloxxado — is a prescription medication that reverses an opioid overdose. While it works quickly, naloxone is a temporary solution that works for 30 to 90 minutes. It’s available both for those who have been prescribed fentanyl and those who are misusing fentanyl. Naloxone may be available without a prescription at community-based programs, local public health groups or local health departments. In many states, the medicine may be requested from a pharmacy without a patient-specific prescription. Deaths from fentanyl — the synthetic, often deadly opioid frequently present in illicit street drugs — have contributed to the United States’ soaring opioid overdose deaths in the last decade.

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- The fentanyl we see in the US drug supply mostly comes from Mexico and China.
- “A lot of people have used drugs that have flowed through cryptomarkets without knowing what cryptomarkets are,” he said.
- Fentanyl is used to treat persistent chronic (long-term) severe pain for those who need constant pain relief and are currently taking other opioid (narcotic) medications.
- Prescriptions written by “cyber doctors” relying on online questionnaires are not legitimate under the law.
- The mortality rates from fentanyl consumption and increasing enforcement actions against dealers have even spooked many cybercriminals into steering clear from facilitating its trade.
Some medical fentanyl is delivered through skin patches, but it is absorbed slowly over the course of hours. These patches can’t quickly deliver a high dose of fentanyl. From April 2024 to March 2025, the CDC reported 43,000 synthetic opioid deaths, most of which are from fentanyl, down from nearly 70,000 in the previous similar period. Fentanyl is a potent opioid that offers pain relief to those who live with severe acute or chronic pain conditions. A healthcare professional may prescribe it to treat severe pain. A person taking prescribed fentanyl can experience dependence, meaning they have withdrawal symptoms when they stop taking the drug.

As with other opioid drugs, fentanyl binds to the receptors in the brain that affect pain and emotion. This causes feelings of well-being (euphoria) and relaxation and relieves pain. The emergency and referral resources listed above are available to individuals located in the United States and are not operated by the National Institute on Drug Abuse (NIDA). NIDA is a biomedical research organization and does not provide personalized medical advice, treatment, counseling, or legal consultation. Information provided by NIDA is not a substitute for professional medical care or legal consultation. This means there must be a real doctor-patient relationship, which by most state laws requires a physical examination.
Additional harm reduction strategies may also be valuable options considering the growing volatility of the drug market. Strategies of going slowly and using with another person can help to prevent overdose deaths. Overdose prevention sites allow individuals to use previously acquired drugs in a safe and supervised space to prevent overdose fatalities (for more on OPS).
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Dealers may sell it as a standalone drug or as a counterfeit for another drug (like oxycodone). It’s also used as a low-cost additive to other drugs like heroin, methamphetamine, molly, and ecstasy. While some opioids come directly from the plant, fentanyl is made in a lab by scientists using the same chemical structure. Do not stop using fentanyl without talking to your doctor. If you suddenly stop using fentanyl, you may experience unpleasant withdrawal symptoms.
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They also had other features suggesting they were untrustworthy. Increasing demand for online pharmaceuticals has in turn raised concerns about the reputability of those who dispense them. ASOP Foundation found that 20 new illicit pharmacy websites are created every day and, in a 2024 survey, found that 54 percent of respondents mistakenly believed that all online pharmacies are FDA approved. The issue of drug safety has come to the fore as more Americans than ever turn to online pharmacies. The liquid form is often dropped on paper or small candy, leading to the potential for tragic deaths among children. Here is what you need to know about fentanyl, what it’s used for, what it does to you, side effects, drug interactions, withdrawal symptoms and why fentanyl is so dangerous.
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There have been situations where people thought they were buying natural products, including weight-loss supplements, cannabis and anti-anxiety medications, and instead got fentanyl-laced drugs. Its strong potency means it can be used in operating rooms, to control pain after surgery and to alleviate pain for people with advanced cancer. But its effectiveness at relieving pain and increasing pleasure also have made it a popular street drug with dangerous risks of addiction, overdose and death. The large number of overdose deaths involving fentanyl highlights the need to ensure people most at risk can access care, as well as the need to expand prevention and response activities.

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Contact a treatment provider today to learn more about your treatment options. Fentanyl is a potent and dangerous drug, and the use of drugs without medical supervision carries significant risks. If you or someone you know is showing these symptoms, it is important to seek professional help immediately. Users and family members should have immediate access to naloxone (Narcan), an opioid agonist medication that rapidly reverses opioid overdose.
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- It works by blocking the effects of opiates to relieve dangerous symptoms caused by high levels of opiates in the blood.
- ASAP Market showing a listing of fentanyl, despite supposedly banning the sale of the drug.
- Sometimes, a person with opioid dependence may take fentanyl as a substitute for heroin.
- It is also increasingly found mixed into street drugs (Drug Enforcement Administration DEA, 2024).
- After use, the patch still contains enough medication to serious harm someone who is not using fentanyl.
If a patient is taking this drug on a prescription basis, they need to communicate immediately with their physician if they experience any adverse effects. Fentanyl + alcohol may increase the risk of respiratory depression and possible overdose. If you unknowingly take fentanyl in another drug, you may overdose since fentanyl is so potent. Withdrawal symptoms typically start within 12 hours after your last dose of the drug.
Store fentanyl in a safe place so that no one else can use it accidentally or on purpose. Use the child-resistant locks and other supplies provided by the manufacturer to keep children away from the lozenges. Keep track of how much fentanyl is left so you will know if any is missing. Store fentanyl at room temperature and away from excess heat and moisture (not in the bathroom). This medication should not be prescribed for other uses; ask your doctor or pharmacist for more information.
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This article focuses on injectable fentanyl; more detailed coverage of the transdermal formulation is available in the StatPearls specific article on transdermal fentanyl. Fentanyl is often mixed with other drugs like heroin, crack, or cocaine. Sometimes people look for combinations of uppers (like crack or cocaine) and downers (like heroin) (this was once called a speedball). Although some people may seek out this combination, dealers may also mix fentanyl into other drugs to stretch their supply and increase their profits. But when fentanyl is mixed into non-opioid drugs (like methamphetamines), or when the dose of fentanyl is higher than an individual is used to, it can be lethal.

In some cases, these illicit formulations of fentanyl are made to look like other prescription opioid tablets. Fentanyl is a powerful opioid pain medication as well as a common contaminant found in illicit drugs. The antidote naloxone (Narcan) can reverse the effects of a fentanyl overdose if given in time.
Fentanyl should be used along with your other pain medication(s). Do not stop taking your other pain medication(s) when you begin your treatment with fentanyl. If you stop taking your other pain medication(s) you will need to stop using fentanyl. Illegal fentanyl can be used in the same ways as prescribed fentanyl.